Atonarp’s LyoSentinel is the industry’s first ever quantitative real time miniaturized molecular sensor and silicon oil protection module for lyophilization (Lyo) process gas detection. Now, you can monitor not only the most minuscule traces of gases, but also the precise quantity of each for optimized process control as well as detect the presence of harmful contaminants. With a rugged Faraday Cup and calibration against the Capacitance Diaphragm Gauge (CDG), the LyoSentinel operates in high pressure environments without the need for external pumps. Its customizable proprietary software puts precision molecular analysis for Lyo applications at your fingertips.
Beyond lyophilization LyoSentinel is being used in applications such as specialty coating and surface treatments.
Compact, sleek and as small, the LyoSentinel can be easily retrofitted onto any freeze-dryer. Ideal for process control applications, it’s fitted with our proprietary miniaturized array of micro-quadrupoles along with integrated small turbo and roughing pumps and the silicon oil detect and protect module.
The LyoSentinel delivers highly accurate measurements due to its innovative electronics and signal processing capability. It performs quantitative molecular scans in less than 10ms, allowing for real-time process control optimization. With its cloud-connected software, you can leverage the data analytics for unparalleled process insight.
Ideal for fast repeatable measurements needed in process control applications, the LyoSentinel spans 6+ decades of concentration dynamic range, down to ppm levels. It is calibrated within the same pressure range against the gold standard Capacitance Diaphragm Gauge (CDG).
Ideal for fast repeatable measurements needed in process control applications, the LyoSentinel spans 6+ decades of concentration dynamic range, down to ppm levels.
With a smart modular design, the LyoSentinel offers the industry’s lowest downtime, with easy on-site replacement of consumable parts and in-built usage diagnostics. Fewer required consumables and low maintenance events translate into a low total cost-of-ownership, and hassle-free operation.
408 x 204 x 316 mmWEIGHT
Miniaturized quadrupole arrays contain smaller rods, and more quadrupoles, than a conventional quadrupole detector.
The standard-sized array is unable to operate at high pressure and requires external vacuum pumps which are space-consuming.
|The LyoSentinel Embedded Mass Spectrometer||Traditional MS|
|Quantitative||Qualitative / Semi-quant|
|Directly calibrated against a Gold Standard||Indirectly by extrapolation, hence inaccurate and requires frequent calibration|
|Can diferentiate between isobaric masses: CO2 (m/z = 44 ) vs. Propane (m/z = 44)||Yes, via its fragmentation ions fingerprinting algorithm|
|Silicone Oil Protection|
|Freeze-dryer sampling pressure||up to 2 Torr|
|Peak resolving capability|
|Quantitative accuracy (%)|
|Automated calibration / tuning|
|21 CFR Part 11|